Cystic Fibrosis Report

 This product is only meant for customers who already 
purchased a Sequencing Test

The Cystic Fibrosis Report is based on Whole Genome Sequencing Test. As such, it analyzes all Common and Rare Variants associated with Cystic Fibrosis instead of a limited set of genes, like old genetic target panels.

Cystic Fibrosis is a multisystem disease affecting epithelia of the respiratory tract, exocrine pancreas, intestine, hepatobiliary system, and exocrine sweat glands. Morbidities include progressive obstructive lung disease with bronchiectasis, frequent hospitalizations for pulmonary disease, pancreatic insufficiency and malnutrition, recurrent sinusitis and bronchitis, and male infertility. Pulmonary disease is the major cause of morbidity and mortality in CF. Meconium ileus occurs at birth in 15%-20% of newborns with CF. More than 95% of males with CF are infertile. Congenital absence of the vas deferens (CAVD) is generally identified during evaluation of infertility or as an incidental finding at the time of a surgical procedure. Hypoplasia or aplasia of the vas deferens and seminal vesicles may occur either bilaterally or unilaterally. Testicular development and function and spermatogenesis are usually normal.

Along with environmental factors, Genetics plays a key role in the regulation of Cystic Fibrosis.

 

• 10 genes analyzed
• 100% genomic regions covered
• Intragenic and intergenic regions analyzed
• All variants reported

 

 

List of genes:

CFTR

FCGR2A

TGFB1

SCNN1A

SCNN1G

SCNN1B

GUCY2C

SLC9A3R1

ATF6

DNASE1